Thyroid hormone actions on male reproductive system of teleost fish

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Thyroid hormones and male reproductive system

Experimental hypothyroidism during sexual development Testes size and number of spermatozoa in adulthood are determined by postnatal/pubertal proliferation of seminal tubule somatic cell constituents, the Sertoli cells. Cessation of proliferation of Sertoli cells during early development occurs concomitantly with formation of their terminally differentiated population. Transient experimental hy...

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Parathyroid hormone-related protein in teleost fish.

A brief description is given of the discovery of PTHrP and the roles of the peptide in mammalian physiology. Next, the occurrence of PTHrP in the earliest vertebrates, sharks, skates and fishes, is reviewed and the calciotropic functions of PTHrP are addressed more specifically in fishes. Parathyroid hormone-related protein (PTHrP) is a hypercalcemic hormone in teleostean fishes, but also has p...

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Molecular cloning and characterization of thyroid hormone receptors in teleost fish.

Thyroid hormones are pleiotropic factors important for many developmental and physiological functions in vertebrates. Their effects are mediated by two specific receptors (TRalpha and TRbeta) which are members of the nuclear hormone receptor superfamily. To clarify the function of these receptors, our laboratory has started a comparative study of their role in teleost fish. This type of approac...

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Thyroid Hormone Transport and Actions

Thyroid hormones (TH) are essential for normal development, differentiation growth and metabolism of every cell in the body. The pro-hormone thyroxine (T4) is synthesized by the thyroid follicles together with a small amount of the biologically active hormone triiodothyronine (T3), which derives mainly from tissue T4 deiodination. Approximately 0.03% of total T4 and 0.3% of total T3 in serum ar...

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ژورنال

عنوان ژورنال: General and Comparative Endocrinology

سال: 2018

ISSN: 0016-6480

DOI: 10.1016/j.ygcen.2018.04.023